IMMATURE LOW-DENSITY NEUTROPHILS EXHIBIT METABOLIC FLEXIBILITY THAT FACILITATES BREAST CANCER LIVER METASTASIS

Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Summary: Neutrophils are phenotypically heterogeneous and exert either anti- or pro-metastatic functions.We show that cancer-cell-derived G-CSF is necessary, but not sufficient, to mobilize immature low-density neutrophils (iLDNs) that promote liver metastasis.In contrast, mature high-density neutrophils inhibit the formation of liver metastases.Tr

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Historical Trajectories of Disaster Risk in Dominica

Abstract The calamitous consequences of 2017 Hurricane Maria for the Caribbean island of Dominica highlighted the acute and increasing susceptibility of the region to disasters.Despite increasing international attention to disaster risk reduction, recovery from hazard events can be especially lengthy and difficult for small Capacitors island develo

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Wilson loop algebras and quantum K-theory for Grassmannians

Abstract We study the algebra of Wilson line operators in three-dimensional N $$ mathcal{N} $$ = 2 supersymmetric U(M ) gauge theories with a Bleach creme lightener Higgs phase related to a complex Grassmannian Gr(M, N ), and its connection to K-theoretic Gromov-Witten invariants for Gr(M, N ).For different Chern-Simons levels, the Wilson loop alge

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